Researchers at medical universities are highly active in scientific collaborations at the national, regional, and international levels. Iranian Medical researchers pay diligent attention to scientific collaborations at all levels. The present study aimed to investigate various dimensions of scientific collaborations of the researchers at Shiraz University of Medical Sciences (SUMS).  The dimensions include the patterns and levels of national and international collaborations, interdisciplinary interactions, the relationship between geographical distance and scientific collaboration, and the interdisciplinarity pattern of international collaborations. The study adopted a descriptive-analytical method. The data were collected using scientometric measures. The research population consisted of 4499 journal articles in Web of Science (WoS) authored by SUMS researchers during 2014-2018. The VOSviewer was applied to analyze the data and visualize the networks. The results revealed that national collaboration was the dominant pattern. The results showed a desirable ratio of scientific collaborations to all publications (52%). The authors mostly tended to collaborate with American researchers. The majority of interdisciplinary collaborations were observed in the microbiology field. The results suggested that geographical distance did not affect scientific collaborations at the national and international levels (P>0.05). At the international level, SUMS researchers had the highest collaboration with the University of Manitoba and Tehran University at the national level. The results suggested that research policymakers at SUMS should prioritize research policies toward scientific collaborations at all levels and fields to share and synergize knowledge.https://dorl.net/dor/20.1001.1.20088302.2021.19.2.3.1